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    ATCC cell lines hek 293t 17 cells atcc crl 11268 kec cells laboratory
    Cell Lines Hek 293t 17 Cells Atcc Crl 11268 Kec Cells Laboratory, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 12205 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cell+lines+hek+293t+atcc/293T%2F17/pm42826711-170-229-234
    Average 99 stars, based on 12205 article reviews
    cell lines hek 293t 17 cells atcc crl 11268 kec cells laboratory - by Bioz Stars, 2026-10
    99/100 stars

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    other:

    Article Title: Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity.
    Article Snippet: Origin Human Serum AB Serotype Gemini Bio Cat# 100-512-100 Sodium Pyruvate GIBCO Cat# 11360070 Penicillin-Streptomycin Sigma-Aldrich Cat# P4458-100ML MEM Vitamin Solution GIBCO Cat# 11120052 HEPES solution,1 M, pH 7.0–7.6 Sigma-Aldrich Cat# H0887-100ML Beta-mercaptoethanol SIGMA Cat# M3148 Recombinant mouse IL-6 protein R&D Systems Cat# 406-ML-005/CF Recombinant mouse IL-23 protein R&D Systems Cat# 11269-ML-010 Recombinant mouse IL-1β protein R&D Systems Cat# 401-ML-005/CF Recombinant human TGFβ1 protein Miltenyi Biotec Cat# 130-095-067 Recombinant human IL-23 protein R&D Systems Cat# 11349-IL-010 Methylprednisolone R&D Systems Cat# 4819/50 Dexamethasone Sigma-Aldrich Cat# D4902 Polyjet SignaGen Laboratories Cat# SL100688 Human TruStain FcXTM (Fc Receptor Blocking Solution) BioLegend Cat# 422302 EBioscience Fixable Viability Dye eFluor 506 Thermo Fisher Scientific Cat# 65-0866-14 Critical commercial assays FoxP3 Transcription Factor Staining Buffer Set Thermo Fisher Scientific Cat# 00-5523-00 Cd4(l3t4) Microbeads, Mouse Miltenyi Biotec Cat# 130-117-043 CD4+ T Cell Isolation Kit, human Miltenyi Biotec Cat# 130-096-533 Deposited data RNA-seq on human T cells This paper GEO: GSE296187 RNA-seq on mouse T cells This paper GEO: GSE296401 scRNA-seq of in vivo Th17 cells Schnell et al.1 GEO: GSE188320 scRNA-seq of in vitro Th17 cells Gaublomme et al.41 GEO: GSE74833 Mass spectrometry proteomics data This paper PRIDE: PXD063778 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-11268 PlatE Cell Biolabs, Inc. Cat# RV-101 Experimental models: Organisms/strains C57BL/6J Jackson laboratory Strain ID: 000664 C57BL/6-Tg(Tcra2D2,Tcrb2D2)1Kuch/J Jackson laboratory Strain ID: 006912 B6.Cg-Tg(Cd4-cre)1Cwi/BfluJ Jackson laboratory Strain ID: 022071 B6.Cg-Tg(Lck-icre)3779Nik/J Jackson laboratory Strain ID: 012837 C57BL/6-Il17atm1Bcgen/J Jackson laboratory Strain ID: 018472 B6.129S7-Rag1tm1Mom/J Jackson laboratory Strain ID: 002216 Chd1fl/fl Jackson laboratory Strain ID: 029262 Nr3c1fl/fl Jackson laboratory Strain ID: 021021 IL-23R-GFP (IL-23R KO) Awasthi et al.49 N/A Recombinant DNA pcDNA3.1 - CHD1 FL This paper N/A pcDNA3.1 - CHD1 Δchro This paper N/A pcDNA3.1 - CHD1 ΔN This paper N/A pcDNA3.1 - STAT3 FL This paper N/A pcDNA3.1 - STAT3 ΔNTD This paper N/A pcDNA3.1 - STAT4 This paper N/A (Continued on next page) Immunity 59, 1–16.e1–e11, August 11, 2026 e3

    Chromatin Immunoprecipitation:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Recombinant:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    Article Title: Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy.
    Article Snippet: Report Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy Graphical abstract Highlights • Engineered scFvs target mutant KRAS with high affinity and specificity in vitro • Oncogenic KRAS directed NeoCARs exhibit anti-tumor response in vitro and in vivo • NeoCARs armored with inducible IL-12 upregulate antigen availability and enhance killing • TCR knockout improves the safety of iIL-12 NeoCARs in vivo Authors Alexander Benton, Jiageng Liu, Mathilde A. Poussin, ..., Matthew D. Beasley, Ben R. Kiefel, Daniel J. Powell, Jr.. Correspondence poda@pennmedicine.upenn.edu In brief Benton et al. identify binders against common mutant KRAS neoantigens and create peptide-centric CAR-T cells (NeoCARs).. NeoCARs demonstrate a robust anti-tumor response against cancer cells expressing mutant KRAS peptides by MHC, both in vitro and in vivo.

    CRISPR:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Plasmid Preparation:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin


    Cloning:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Software:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    In Vivo Imaging:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    SPR Assay:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Cell Surface Hydrophobicity:

    Article Title: Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin.
    Article Snippet: Article Vaginal microbiota transfer ameliorates cesareanassociated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

    Enzyme-linked Immunosorbent Assay:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    RNA Sequencing:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Article Title: A pancreatic cancer organoid biobank links multi-omics signatures to therapeutic response and clinical evaluation of statin combination therapy.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER KU-55933 TargetMol Cat# T2685 Ralimetinib dimesylate TargetMol Cat# T6047 SU5402 TargetMol Cat# T6996 Axitinib TargetMol Cat# T1452 Letrozole TargetMol Cat# T1590 Irbinitinib(Tucatinib) TargetMol Cat# T2364 Erdafitinib TargetMol Cat# T3726 Trametinib TargetMol Cat# T2125 Dabrafenib TargetMol Cat# T1903 Wortmannin TargetMol Cat# T6283 Lovastatin TargetMol Cat# T1207 Fulvestrant TargetMol Cat# T2146 Nilutamide TargetMol Cat# T0272 Bicalutamide TargetMol Cat# T0380 Cytarabine TargetMol Cat# T1272 Pomalidomide TargetMol Cat# T2384 Lenalidomide TargetMol Cat# T1642 Pitavastatin calcium TargetMol Cat# T2534 Rapamycin TargetMol Cat# T1537 RHPS4 TargetMol Cat# T6967 BIBR 1532 TargetMol Cat# T2380 10058-F4 TargetMol Cat# T3048 Danusertib TargetMol Cat# T2094 Pazopanib TargetMol Cat# T0097L Sunitinib TargetMol Cat# T0374L Erlotinib TargetMol Cat# T0373 Ilorasertib TargetMol Cat# TQ0059 Pralsetinib TargetMol Cat# TQ0277 Tipifarnib TargetMol Cat# T6271 Defactinib TargetMol Cat# T1996 GSK2256098 TargetMol Cat# T2281 Selumetinib TargetMol Cat# T6218 Vemurafenib TargetMol Cat# T2382 Encorafenib TargetMol Cat# T6487 LY294002 TargetMol Cat# T2008 Alpelisib TargetMol Cat# T1921 Capivasertib TargetMol Cat# T1920 Everolimus TargetMol Cat# T1784 BLU2864 TargetMol Cat# T60170 Vismodegib TargetMol Cat# T2590 Erismodegib(Sonidegib) TargetMol Cat# T1926 Olaparib TargetMol Cat# T3015 Niraparib TargetMol Cat# T3231 Mirdametinib TargetMol Cat# T6189 10074-G5 TargetMol Cat# T3686 Poziotinib TargetMol Cat# T2630 Regorafenib TargetMol Cat# T1792 Lapatinib TargetMol Cat# T0078 Foretinib TargetMol Cat# T3113 (Continued on next page) Cell Stem Cell 32, 1369–1389.e1–e14, September 4, 2025 e2 .. REAGENT or RESOURCE SOURCE IDENTIFIER Cobimetinib TargetMol Cat# T3623 Sorafenib TargetMol Cat# T0093L Dinaciclib(CDK inhibitor) TargetMol Cat# T1912 Tunicamycin TargetMol Cat# T13229 Afatinib TargetMol Cat# T21312 AZD7762 TargetMol Cat# T6093 capecitabine Selleck chemicals Cat# S1156 cisplatin Selleck chemicals Cat# S1166 Doxorubicin Selleck chemicals Cat# E2516 5-FU Selleck chemicals Cat# S1209 Oxaliplatin Selleck chemicals Cat# S1224 Irinotecan Selleck chemicals Cat# S1198 Gemcitabine Selleck chemicals Cat# S1714 Paclitaxel Selleck chemicals Cat# S1150 R428 Selleck chemicals Cat# S2841 BB-94 Selleck chemicals Cat# S7155 Sotorasib TargetMol Cat# T8684 TNO115 TargetMol Cat# T13176 BAY-293 TargetMol Cat# T5418 NSC319726 TargetMol Cat# T2464 P53R3 TargetMol Cat# T41068 SCH529074 TargetMol Cat# T37042 COTI-2 TargetMol Cat# T4325 PRIMA-1 TargetMol Cat# T6954 MRTX-9768 TargetMol Cat# T9575 MS37452 TargetMol Cat# T21767 Kartogenin TargetMol Cat# T1748 SGN-2FF TargetMol Cat# T12894 Lith-O-Asp MCE Cat# T11858 atorvastatin Selleck chemicals Cat# T3116 DMSO Innoche Cat# D3850-500ML Deposited data Whole genome sequencing data This study GSA: HRA007290 and NODE: OEP004966 RNA-seq data This study GSA: HRA007290 and NODE: OEP004966 ATAC-seq data This study GSA: HRA007290 and NODE: OEP004966 Proteomic data This study OMIX: OMIX009187 Phosphoproteomic data This study OMIX: OMIX006355 Glycoproteomic data This study OMIX: OMIX009209 Histological images This study OMIX: OMIX009185 Processed proteomic data Hyeon et al.35 PDC: PDC000248 Processed proteomic and glycoproteomic data Cao et al.36 LinkedOmics: http://www.linkedomics.org/data_ download/CPTAC-PDAC/ Experimental models: Cell lines HEK-293T ATCC Cat# CRL-1573 Experimental models: Organisms/strains Human PDAC organoids This study N/A DH5α AlpaLifeBio KTSM101L (Continued on next page) e3 Cell Stem Cell 32, 1369–1389.e1–e14, September 4, 2025 ..

    Quantitative RT-PCR:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Mutagenesis:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..


    SYBR Green Assay:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    In Vivo:

    Article Title: Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Mouse TNF-α ELISA Elabscience Cat# E-EL-M3063 Mouse TGF-β1 ELISA Elabscience Cat# E-EL-M0051 Deposited data RNA-seq data This paper GEO: GSE271032 ChIP-seq This paper GEO: GSE271032 Experimental models: Cell lines HEK 293T ATCC Cat# CRL-3216; RRID: CVCL_0063 Bone Marrow-Derived Macrophage This paper N/A Experimental models: Organisms/strains Ets1-loxp mice This paper N/A db/db mice The JacksonL aboratory Cat# JAX:000642; RRID: IMSR_JAX:000642 C57BL/6Jmice The JacksonL aboratory Cat# JAX:000664; RRID: IMSR_JAX:000664 Oligonucleotides Primers used for cloning and qRT-PCR in this study are listed in Table S3 This paper N/A Recombinant DNA PCMV-myc-Ets1 This paper N/A Ets1 T38A mutant This paper N/A Ets1-promoter This paper N/A IRF4-promote This paper N/A IRF4-promote ΔEBS This paper N/A Software and algorithms FlowJo v11.1 TreeStar https://www.flowjo.com/flowjo/download Trimmomatic Bolger et al. 52 http://www.usadellab.org/cms/index. php?page=trimmomatic; RRID: SCR_011848 ImageJ NIH https://imagej.nih.gov/ij/ GraphPad Prism v8 GraphPad https://www.graphpad.com/guides/prism/ 8/userguide/tips_for_using_prism.htm Adobe Illustrator Adobe https://www.adobe.com/cn/ Other High fat diet Research Diets Cat# D12492 SYBR Green Mix Vazyme Cat# Q111-02 16 Cell Reports 45, 117244, April 28, 2026 Animal sample size and sex details To minimize intrinsic variability in metabolic phenotypes, male mice were exclusively utilized for all in vivo experiments. ..

    Double Staining:

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    CCK-8 Assay:

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    Cytotoxicity Assay:

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    Bicinchoninic Acid Protein Assay:

    Article Title: Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4 QTY -Fc as a molecular trap.
    Article Snippet: Technology Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

    Sequencing:

    Article Title: A pancreatic cancer organoid biobank links multi-omics signatures to therapeutic response and clinical evaluation of statin combination therapy.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER KU-55933 TargetMol Cat# T2685 Ralimetinib dimesylate TargetMol Cat# T6047 SU5402 TargetMol Cat# T6996 Axitinib TargetMol Cat# T1452 Letrozole TargetMol Cat# T1590 Irbinitinib(Tucatinib) TargetMol Cat# T2364 Erdafitinib TargetMol Cat# T3726 Trametinib TargetMol Cat# T2125 Dabrafenib TargetMol Cat# T1903 Wortmannin TargetMol Cat# T6283 Lovastatin TargetMol Cat# T1207 Fulvestrant TargetMol Cat# T2146 Nilutamide TargetMol Cat# T0272 Bicalutamide TargetMol Cat# T0380 Cytarabine TargetMol Cat# T1272 Pomalidomide TargetMol Cat# T2384 Lenalidomide TargetMol Cat# T1642 Pitavastatin calcium TargetMol Cat# T2534 Rapamycin TargetMol Cat# T1537 RHPS4 TargetMol Cat# T6967 BIBR 1532 TargetMol Cat# T2380 10058-F4 TargetMol Cat# T3048 Danusertib TargetMol Cat# T2094 Pazopanib TargetMol Cat# T0097L Sunitinib TargetMol Cat# T0374L Erlotinib TargetMol Cat# T0373 Ilorasertib TargetMol Cat# TQ0059 Pralsetinib TargetMol Cat# TQ0277 Tipifarnib TargetMol Cat# T6271 Defactinib TargetMol Cat# T1996 GSK2256098 TargetMol Cat# T2281 Selumetinib TargetMol Cat# T6218 Vemurafenib TargetMol Cat# T2382 Encorafenib TargetMol Cat# T6487 LY294002 TargetMol Cat# T2008 Alpelisib TargetMol Cat# T1921 Capivasertib TargetMol Cat# T1920 Everolimus TargetMol Cat# T1784 BLU2864 TargetMol Cat# T60170 Vismodegib TargetMol Cat# T2590 Erismodegib(Sonidegib) TargetMol Cat# T1926 Olaparib TargetMol Cat# T3015 Niraparib TargetMol Cat# T3231 Mirdametinib TargetMol Cat# T6189 10074-G5 TargetMol Cat# T3686 Poziotinib TargetMol Cat# T2630 Regorafenib TargetMol Cat# T1792 Lapatinib TargetMol Cat# T0078 Foretinib TargetMol Cat# T3113 (Continued on next page) Cell Stem Cell 32, 1369–1389.e1–e14, September 4, 2025 e2 .. REAGENT or RESOURCE SOURCE IDENTIFIER Cobimetinib TargetMol Cat# T3623 Sorafenib TargetMol Cat# T0093L Dinaciclib(CDK inhibitor) TargetMol Cat# T1912 Tunicamycin TargetMol Cat# T13229 Afatinib TargetMol Cat# T21312 AZD7762 TargetMol Cat# T6093 capecitabine Selleck chemicals Cat# S1156 cisplatin Selleck chemicals Cat# S1166 Doxorubicin Selleck chemicals Cat# E2516 5-FU Selleck chemicals Cat# S1209 Oxaliplatin Selleck chemicals Cat# S1224 Irinotecan Selleck chemicals Cat# S1198 Gemcitabine Selleck chemicals Cat# S1714 Paclitaxel Selleck chemicals Cat# S1150 R428 Selleck chemicals Cat# S2841 BB-94 Selleck chemicals Cat# S7155 Sotorasib TargetMol Cat# T8684 TNO115 TargetMol Cat# T13176 BAY-293 TargetMol Cat# T5418 NSC319726 TargetMol Cat# T2464 P53R3 TargetMol Cat# T41068 SCH529074 TargetMol Cat# T37042 COTI-2 TargetMol Cat# T4325 PRIMA-1 TargetMol Cat# T6954 MRTX-9768 TargetMol Cat# T9575 MS37452 TargetMol Cat# T21767 Kartogenin TargetMol Cat# T1748 SGN-2FF TargetMol Cat# T12894 Lith-O-Asp MCE Cat# T11858 atorvastatin Selleck chemicals Cat# T3116 DMSO Innoche Cat# D3850-500ML Deposited data Whole genome sequencing data This study GSA: HRA007290 and NODE: OEP004966 RNA-seq data This study GSA: HRA007290 and NODE: OEP004966 ATAC-seq data This study GSA: HRA007290 and NODE: OEP004966 Proteomic data This study OMIX: OMIX009187 Phosphoproteomic data This study OMIX: OMIX006355 Glycoproteomic data This study OMIX: OMIX009209 Histological images This study OMIX: OMIX009185 Processed proteomic data Hyeon et al.35 PDC: PDC000248 Processed proteomic and glycoproteomic data Cao et al.36 LinkedOmics: http://www.linkedomics.org/data_ download/CPTAC-PDAC/ Experimental models: Cell lines HEK-293T ATCC Cat# CRL-1573 Experimental models: Organisms/strains Human PDAC organoids This study N/A DH5α AlpaLifeBio KTSM101L (Continued on next page) e3 Cell Stem Cell 32, 1369–1389.e1–e14, September 4, 2025 ..

    Luciferase:




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